Our Mission
Wisdom At Scale
Written by Wey Xie, Founder & CEO
August 2025
We founded Ontosyn because we recognized a profound asymmetry defining our era: our technological capabilities advance exponentially while our capacity for wise application lags dangerously behind. Climate models grow more sophisticated each year, yet implementation of climate solutions remains fragmented across jurisdictional and disciplinary boundaries. Medical researchers generate breakthrough insights at unprecedented rates, yet the average time from discovery to clinical application remains 17 years. Meanwhile, artificial intelligence systems approach and exceed human performance in narrow domains, often without our understanding of their decision-making processes or societal implications.
This acceleration-wisdom gap stems fundamentally from how we organize and distribute human knowledge. The scientific enterprise—humanity's most systematic attempt at understanding reality—has become constrained by structural inefficiencies that impede the very progress it seeks to enable. Today, over 2.5 million peer-reviewed papers are published annually across approximately 30,000 journals, creating an information landscape that no individual researcher can meaningfully navigate. Critical insights remain siloed within hyper-specialized communities, while interdisciplinary synthesis—often where breakthrough understanding emerges—becomes increasingly difficult.
The contemporary academic publishing system exemplifies these structural challenges. Despite the negligible marginal cost of digital distribution, most research remains locked behind paywalls that generate over $10 billion in annual revenue for publishers while providing minimal value to researchers or society. Peer review processes, originally designed for a smaller, more manageable volume of research, now create bottlenecks that delay important findings by 12-18 months on average. The "publish or perish" incentive structure rewards quantity and novelty over replication, verification, and synthesis, contributing to what many consider a reproducibility crisis: recent meta-analyses suggest that fewer than 40% of published findings in psychology and medicine can be reliably reproduced.
Perhaps most critically, the current system has evolved into what sociologist Pierre Bourdieu would recognize as a "prestige economy"—where success is measured primarily by citations, journal rankings, and grant funding rather than genuine contribution to human understanding or societal benefit. Researchers increasingly optimize for metrics that correlate weakly with research quality or impact: journal impact factors that can be gamed, citation counts that favor self-referential communities, and funding acquisition that often rewards conservative approaches over transformative inquiry. This misalignment of incentives diverts substantial intellectual resources away from the fundamental work of discovery and understanding.
Yet within these challenges lies extraordinary opportunity. The same technologies that have accelerated our capabilities can be harnessed to reorganize how we create, validate, and distribute scientific knowledge. Large language models demonstrate unprecedented ability to synthesize information across vast corpora, identify patterns spanning multiple domains, and generate novel hypotheses. When properly designed and deployed, AI systems can serve not as replacements for human judgment but as amplifiers of human insight—enabling researchers to engage more deeply with literature, identify unexpected connections, and focus their cognitive resources on the uniquely human work of creative interpretation and meaning-making.
We envision a future where scientific understanding flows efficiently through global research communities: where a climate researcher in Bangladesh can instantly access and synthesize findings from atmospheric physicists in Colorado and marine biologists in Norway; where medical researchers can identify drug repurposing opportunities by connecting molecular mechanisms studied in disparate therapeutic contexts; where philosophers and cognitive scientists can collaborate seamlessly to address questions about consciousness and artificial intelligence that neither discipline can resolve in isolation.
This vision requires infrastructure—not merely technological but institutional. Nova represents our initial contribution: an AI-powered research platform that enables individual researchers and scientific teams to engage more deeply with literature while maintaining the critical thinking and scholarly rigor that define excellent research. Nova is built on Nexus, our comprehensive, continuously updated corpus of scientific literature, processed through AI systems designed to respect the complexity and nuance of scientific knowledge while making it more accessible and actionable.
Our ultimate goal extends beyond improved productivity to structural reform: realigning incentives to reward genuine contribution over symbolic achievements, democratizing access to the full corpus of human knowledge, and enabling the kind of large-scale synthesis that could guide humanity toward wiser decision-making. The challenges facing our species—from climate change to artificial intelligence alignment to global health equity—require not just more research but better integration of what we already know. This is the work of wisdom at scale, and it begins with reforming how humanity creates, validates, and shares scientific knowledge.